CCMAS Course Search

Introduction, basic definitions, aetiology of disease. Cell injury, cellular adaptation, cell death (necrosis and apoptosis). Free radicals. Ischemic cell injury. Cutaneous wound healing and repair. Inflammation, definition and causes of acute inflammation. Vascular and cellular events in acute inflammation. Mediators of acute inflammation (vaso-active amines, plasma derived). Serous/fibrinous inflammation, chronic inflammation, granulomatous inflammation. Systemic effects of inflammation. Consequences of deficient/excess inflammation. Genetic disorders, classification (chromosomal, single gene and multifactorial). Chromosomal disorders (Down, Turner, Klinefelter, Edwards syndromes). Single gene disorders (classic and non classic). Mutations and multifactorial disorders. Congenital anomalies, types, aetiology. Teratogenesis.

Introduction, basic definitions, aetiology of disease. Cell injury, cellular adaptation, cell death (necrosis and apoptosis). Free radicals. Ischemic cell injury. Cutaneous wound healing and repair. Inflammation, definition and causes of acute inflammation. Vascular and cellular events in acute inflammation. Mediators of acute inflammation (vaso-active amines, plasma derived). Serous/fibrinous inflammation, chronic inflammation, granulomatous inflammation. Systemic effects of inflammation. Consequences of deficient/excess inflammation. Genetic disorders, classification (chromosomal, single gene and multifactorial). Chromosomal disorders (Down, Turner, Klinefelter, Edwards syndromes). Single gene disorders (classic and non classic). Mutations and multifactorial disorders. Congenital anomalies, types, aetiology. Teratogenesis.

Immunopathology. Innate and adaptive immunity. Components of immune system (cells, tissues and molecules). Hypersensitivity disorders. Major histocompatibility complex. Mechanism of tolerance. Autoimmunity. Primary immunodeficiencies. AIDS. Amyloidosis. Haemodynamic disorders. Oedema. Embolism. Thrombosis. Shock. Neoplasia. Definition, benign/malignant tumours. Tumour nomenclature, aetiology of tumours. Genes involved in neoplastic process. Familial syndromes. Chemical, radiation and microbial carcinogenesis. Tumour immunity. Effect of tumour on host. Paraneoplastic syndromes. Intracellular accumulations. Pathologic calcification. Intracellular accumulations of protein. Lipids, glycogen and pigments. Infectious diseases. Malaria. Tuberculosis. Leprosy. Schistosomiasis. Syphilis. Amoebiasis. Typhoid. Onchocerciasis.

Immunopathology. Innate and adaptive immunity. Components of immune system (cells, tissues and molecules). Hypersensitivity disorders. Major histocompatibility complex. Mechanism of tolerance. Autoimmunity. Primary immunodeficiencies. AIDS. Amyloidosis. Haemodynamic disorders. Oedema. Embolism. Thrombosis. Shock. Neoplasia. Definition, benign/malignant tumours. Tumour nomenclature, aetiology of tumours. Genes involved in neoplastic process. Familial syndromes. Chemical, radiation and microbial carcinogenesis. Tumour immunity. Effect of tumour on host. Paraneoplastic syndromes. Intracellular accumulations. Pathologic calcification. Intracellular accumulations of protein. Lipids, glycogen and pigments. Infectious diseases. Malaria. Tuberculosis. Leprosy. Schistosomiasis. Syphilis. Amoebiasis. Typhoid. Onchocerciasis.

General Pharmacology: Historical development of pharmacology; divisions of pharmacology and their applications; definitions of terms and abbreviations: concept and nature of drugs. Pharmacodynamics; pharmacokinetics; classification of drugs and their importance. Drug abuse and control; drug noncompliance or misuse. Toxicology: Introduction to toxicology and its importance; general principles of poison managements.

General principles of pharmacology. Definition of basic concepts in pharmacology: pharmacy, pharmacognosy, pharmacotherapeutics, toxicology and many others. Drug administration: methods and absorption of drugs; distribution; biotransformation and excretion of drugs. Drug receptor interaction; dose - response relationship. Fate of systemically administered drugs. Autonomic nervous system pharmacology: principles and classification of autonomic drugs; Anti- inflammatory drugs; Chemotheraphy agents. Action of drugs, factors influencing it. Compatibility and incompatibility, tolerance, tachyphylaxis, potentiation, synergism, additive, antagonism and many others.

History of Pharmacology and its development. Introduction to pharmacokinetics; drug absorption and bioavailability. Drug metabolism, pharmaco-genetics. Effects of disease on drug kinetics. Drug in pregnancy and the extreme age. Pharmacodynamics; dose-response relationships, LD50 ED50 and TD50. Therapeutic index; introduction of new drugs, clinical trials; adverse drug reactions and adverse reaction surveillance. Routes of drug administration. Basic principles of pharmacokinetics. Absorption, distribution and biotransformation of drugs. Drug reception interactions. Non-Steroidal Anti-inflammatory Drugs (NSAID). Muscle relaxants, sedatives and analgesic agents. Anti-hypertensive drugs. Bronchodilators and many others.

History of Pharmacology and its development. Introduction to pharmacokinetics; drug absorption and bioavailability. Drug metabolism, pharmaco-genetics. Effects of disease on drug kinetics. Drug in pregnancy and the extreme age. Pharmacodynamics; dose-response relationships, LD50 ED50 and TD50. Therapeutic index; introduction of new drugs, clinical trials; adverse drug reactions and adverse reaction surveillance. Routes of drug administration. Basic principles of pharmacokinetics. Absorption, distribution and biotransformation of drugs. Drug reception interactions. Non-Steroidal Anti Inflammatory Drugs (NSAID). Muscle relaxants, sedatives and analgesic agents. Anti- hypertensive drugs. Bronchodilators and many others.

Space and time. Units and dimension. Vectors and scalars. Differentiation of vectors. Displacement, velocity and acceleration. Kinematics, Newton laws of motion (Inertial frames, Impulse, force and action at a distance, momentum conservation). Relative motion. Application of Newtonian mechanics, equations of motion, conservation principles in physics, conservative forces, conservation of linear momentum, kinetic energy and work. Potential energy, system of particles and centre of mass. Rotational motion; Torque, vector product, moment, rotation of coordinate axes and angular momentum. Polar coordinates, conservation of angular momentum and circular motion. Moments of inertia, gyroscopes and precession. Gravitation: Newton’s law of gravitation, Kepler’s Laws of planetary motion, gravitational potential energy, escape velocity, satellites motion and orbits.

Space and time; units and dimension, Vectors and Scalars, Differentiation of vectors: displacement, velocity and acceleration; kinematics; Newton laws of motion (Inertial frames, Impulse, force and action at a distance, momentum conservation); Relative motion; Application of Newtonian mechanics; Equations of motion; Conservation principles in physics, Conservative forces, conservation of linear momentum, Kinetic energy and work, Potential energy, System of particles, Centre of mass; Rotational motion; Torque, vector product, moment, rotation of coordinate axes and angular momentum. Polar coordinates; conservation of angular momentum; Circular motion; Moments of inertia, gyroscopes and precession; Gravitation: Newton’s Law of Gravitation, Kepler’s Laws of Planetary Motion, Gravitational Potential Energy, Escape velocity, Satellites motion and orbits.