Course Gaps at Institute of Management and Technology (IMT), Enugu

Classification and nomenclature of enzymes; Isolation and purification of enzymes; Specificity of enzymes action; Kinetics of single substrate enzyme catalyzed reaction; Enzyme inhibitions; Kinetics of multi-substrate enzyme-catalyzed reaction; Investigations of the structures of active site of enzymes; Applications of enzyme technology; immobilized enzymes; Use of enzymes in industries; medicine; agriculture etc; Ligand binding; Kinetics of multi-binding sites; Adair's equation; Sigmoidal kinetics and allosteric enzymes; MWC and KNF models of allosteric regulation; Sigmoidal kinetics in the absence of cooperative binding; Kinetics of fast reactions; Structure and mechanism of catalysis; Recent Advances in enzyme Technology

Introductory chemistry of amino acids; their properties, reactions and biological functions. Classification of amino acids: neutral, basic and acidic; polar and non-polar; essential and non- essential amino acids. Peptides. Introductory chemistry and classification of proteins. Biological functions of proteins. Methods of their isolation, purification and identification. Primary, secondary, tertiary and quaternary structures of proteins. Basic principles of tests for proteins and amino acids. Introductory chemistry of carbohydrates, lipids and nucleic acids. Nomenclature of nucleosides, and nucleotides; effects of acid and alkali on hydrolysis of nucleic acids.

Introductory chemistry of amino acids, their properties, reactions and biological functions. Classification of amino acids: neutral, basic and acidic; polar and non-polar; essential and non- essential amino acids. Peptides. Introductory chemistry and classification of proteins. Biological functions of proteins. Methods of their isolation, purification and identification. Primary, secondary, tertiary and quaternary structures of proteins. Basic principles of tests for proteins and amino acids. Introductory chemistry of carbohydrates, lipids and nucleic acids. Nomenclature of nucleosides and nucleotides, effects of acid and alkali on hydrolysis of nucleic acids.

The cell theory. Structures and functions of major cell components. Cell types, constancy and diversity. Cell organelles of prokaryotes and eukaryotes. Chemical composition of cells. Centrifugation and methods of cell fractionation. Structure, function and fractionation of extra- cellular organelles. Water, total body water and its distribution. Regulation of water and electrolyte balance. Disorder of water and electrolyte balance. Acidity and alkalinity, pH and pK values and their effects on cellular activities.