CCMAS Course Search

Historical survey of the development and importance of organic chemistry, fullerenes as fourth allotrope of carbon, uses as nanotubules, nanostructures and nano chemistry. Electronic theory in organic chemistry. Isolation and purification of organic compounds. Determination of structures of organic compounds including qualitative and quantitative analysis in organic chemistry. Nomenclature and functional group classes of organic compounds. Introductory reaction mechanism and kinetics. Stereochemistry. The chemistry of alkanes, alkenes, alkynes, alcohols, ethers, amines, alkyl halides, nitriles, aldehydes, ketones, carboxylic acids and derivatives. The chemistry of selected metals and non-metals. Comparative chemistry of group IA, IIA and IVA elements. Introduction to transition metal chemistry.

Laboratory experiments designed to reflect topics presented in courses CHM 101 and CHM 102. These include acid-base titrations, qualitative analysis, redox reactions, gravimetric analysis, data analysis and presentation.

Continuation of CHM 107. Additional laboratory experiments to include functional group analysis, quantitative analysis using volumetric methods.

Gametogenesis. Cyclic changes in the female genital tract. Fertilization, cleavage, blastocyst, gastrulation and formation of germ layers. Segmentation of mesoderm. Folding of embryo foetal membranes. Umbilical cord and placentation. Development of limbs and teratology. Developmental anomalies and their clinical syndromes.

Evaluation of the gynaecologic patient. Gynaecologic history, gynaecologic physical examination, common laboratory tests in gynaecology, imaging techniques, surgical evaluation in gynaecology. Paediatric gynaecology, congenital anomaly of the female genital tract, intersex disorders, acquired gynaecological disorders of childhood. Endometriosis and adenomyosis, chronic pelvic pain, genital tract injuries, dilatation and curettage, acquired gynaetresia, intermenstrual, post coital and post-menopausal bleeding, ectopic gestation, displacements of the female genitalia. Medical ethics in gynaecology-historical perspective of medical ethics, forensic medicine and litigation in gynaecology, informed consent, sick leave, death certificate, abortion, rape, incest and gender-based violence.

Blood cell formation and regulation. Erythropoiesis, myelopoiesis, lymphopoiesis and thrombopoiesis. Growth factors in haematopoiesis. Genetic control of haemoglobin synthesis. Sites of haematopoiesis in the foetus and in adult life. Types of prenatal and postnatal haemoglobins. Normal haematological values, red cell count, HB concentration, Haematocrit. Red cell indices. MCV, MCH, MCHC, correlation with red cell morphology/ morphological classification of anaemia. White cell count, differentials and absolute counts, platelet count. Quantitative blood cell abnormalities, anaemia vs polycythaemia, causes/mechanism/clinical/evaluation. Leucocytosis/leucopoenia causes/mechanism/clinical evaluation. Thrombocytosis Vs thrombocytopaenia, causes/ mechanism/clinical evaluation. Qualitative blood cell Abnormalities. Revise normal structure and functions of red blood cells, leucocytes and platelets. Red cell shape abnormalities. Red cell size abnormalities. Red cell inclusions. White cell nuclear abnormalities. White cell cytoplasmic inclusions and abnormalities. Platelet size abnormalities. Lymphadenopathy-causes/characterisation/clinical evaluation. Splenomegaly, hypersplenism, hyperreactive, malarial, splenomegaly, causes, characterisation, clinical evaluation. Hyposplenism and splenectomy. Causes, characterisation, clinical, evaluation. Causes of functional asplenia/hyposplenism and surgical splenectomy. Precautions and treatment. 83

Iron sources, absorption, transportation, storage and metabolism. Deficiency anaemia. Iron overload, haemosiderosis/haemochromatosis. Megaloblastic anaemias. Sources, absorption, transportation and storage of folates and vitamin B12. Folate deficiency. Vitamin B12 deficiency, clinical features, laboratory findings, diagnosis and treatment. Aplastic anaemia, myelopathic anaemia and leucoerythroblastic anaemia. Anaemia of chronic diseases. Chronic infections. Chronic inflammation. Clinical and laboratory features. Differential diagnoses. General aspects of haemolytic anaemias. Definition, types. Intravascular and extravascular haemolysis and their clinical and biochemical features. Inherited vs acquired. Haemoglobinopathies. Sickle cell diseases, thalassemia, genetic counselling, antenatal diagnosis of haemoglobinopathies. Red cell membranopathies, Spherocytosis, elliptocytosis, stomatocytosis. Others. Red cell enzymopathies. G6PD deficiency, pyruvate kinase deficiency. Acquired haemolytic anaemias, auto immune. Warm/cold. Microangiopathy. Mechanical contact anaemia. Red cell infections-malaria.

Introduction to medical mycology. Nature and classification of medically important fungi. Mode of reproduction of fungi.

Taxonomy of parasites. Historical development of medical protozoology. Development of medical helminthology. Classification of Helminthes. General properties of Helminthes.

Introduction, basic definitions, aetiology of disease. Cell injury, cellular adaptation, cell death (necrosis and apoptosis). Free radicals. Ischemic cell injury. Cutaneous wound healing and repair. Inflammation, definition and causes of acute inflammation. Vascular and cellular events in acute inflammation. Mediators of acute inflammation (vaso-active amines, plasma derived). Serous/fibrinous inflammation, chronic inflammation, granulomatous inflammation. Systemic effects of inflammation. Consequences of deficient/excess inflammation. Genetic disorders, classification (chromosomal, single gene and multifactorial). Chromosomal disorders (Down, Turner, Klinefelter, Edwards syndromes). Single gene disorders (classic and non classic). Mutations and multifactorial disorders. Congenital anomalies, types, aetiology. Teratogenesis.