Course Gaps at Abia State University, Uturu

Descriptive terms, plans and terms of relationship of the human body, terms of comparison, attachment of muscles, types of muscles, movements of joints. Osteology, principles of kinesiology, general organisation of body system. Cutaneous innervation of the upper limb; pectoral region; breast; axilla; shoulder region; arm and cubital fossa; flexor compartment of forearm; extensor compartment of forearm; hand; venous and lymphatic drainage of the upper limb. Applied anatomy of nerves; blood supply of the upper limb. Cutaneous innervation of the lower limb; femoral triangle; adductor canal and medial side of the thigh; gluteal region; back of the thigh, popliteal fossa; extensor compartment of the leg and dorsum of the foot; peroneal and flexor compartment of the leg; sole of the foot, arches of the foot; mechanism of walking; venous and lymphatic drainage of the lower limb; applied anatomy of the nerves and blood supply to the lower limb.

Introduction - Theory of Chemical Neurotransmission Evidence for Acetylcholine as a Cholinergic neurotransmitter. Detection and Bioassay of acetylcholine. Cholinergic receptors, sites of action of acetylcholine at the Neuromuscular junction. Agonists and antagonists of cholinergic transmission. Parasympathomimetic and parasympatholytic drugs. Structure – Activity Relationships among the cholinergic and anticholinergic agents. Cholinesterases and anti- cholinesterases. Properties and uses of anti-cholinesterases (reversible and irreversible). Brief mention of cholinesterase reactivators (pralidoxime, obidoxime) and their uses. Neuromuscular transmission and drugs which enhance neuromuscular transmission. Neuromuscular Blockade. Smooth muscle relaxants. Ganglion stimulation and blockade and their properties.

Fundamental and derived quantities and units. Equation of motion, concepts of force work energy, power, momentum energy conservation. Fields, Electrostatics, Physical Factors governing capacitance, charging and discharging capacitor and their uses in Radiological Equipment, basic x-ray circuitry and many others. Basic computer Architecture and peripherals. Electromagnetic and Electromagnetic induction, Lenz laws, Mutual and Self-induction. principles and construction of the transformer. Transformer Parameters, uses of mutual and self-inductance in autotransformers and High Tension transformers, AC theory and sources of electric power supply. current electricity, solid state devices, Rectification, principles and uses in Radiology, concept of energy. Atomic structure, Bohr’s atom elements of quantum mechanics applied to atom, Heisenberg’s uncertainty theory, de Broglie wavelength, Schrodinger equation and configuration of atoms. The nuclear structure and models, nuclear instability and radioactivity, Wave and Quantum methods of Energy Transfer and applications in radiology, production of X-rays, Radioactivity and radioactive decay, half-life, counters, units of activity and measurement, K- capture. The atom, isotopes, isobars, isomers, nuclear binding energies, and inverse square law, effects of filtration. Luminescence and their applications. Interaction of radiation (emr and particulate radiation) with matter and their applications in medical imaging and radiotherapy. Attenuation of radiation shielding and filtration.

Ophthalmic lens manufacture; Lens surfacing, polishing and glazing techniques; Grinding of prismatic and cylindrical lenses. Edging, insertion of lenses into frames. Front bench spectacle works and verification; patient fitting; ophthalmic frames, facial measurement and selection based on frame sizes. Format making; marking and placement of optical centres; bifocals and multifocal segments. Spectacle adjustments and repairs. Manufacture of contact lenses and ocular prosthesis. Laboratory sessions are included.

Nursing Charts: Methods of taking/recording patient’s temperature, pulse, respiration: BP. Bed making: Prevention of bedsores: General skin care: Sterile dressing/bandaging, wound management, Nursing procedures in the management of surgical patients, Nursing procedures in ICU, management of ICU patients, Lifting techniques – lifting of patients: Intramuscular/Intravenous drug administration. Injection: Chemotherapy/Medication procedure on the wards, palliative care nursing: Nurse – Therapist relationship: Practical/Clinical Sessions.

Introduction: Medicines and discovery processes. Initial stages: Target discovery; applications of molecular biology, in silico methods and assays; lead discovery; lead optimization; biomarkers. Measurement of drug properties: assay techniques; agonists (full, partial, inverse and biased); competitive antagonists. In vivo models; pharmacokinetic profiles of compounds; pharmacogenetics and formulations. Pre-clinical safety assessment including acute toxicity evaluation, subacute and chronic toxicity studies, reproductive toxicity, carcinogenicity studies, mutagenicity and mechanistic toxicity studies. Limitations of preclinical studies. Problems associated with drug discovery and development. Later stages: Pharmaceutical development; phases of clinical evaluation; ethics (informed consent, good clinical practice, participation criteria, sponsorship) and concepts in clinical trial design. Pharmacovigilance. e-Learning Activity Links are provided to additional resources (further reading, videos, on-line activities) to support the lecture content. Online self-assessment modules on the course content can be provided for formative feedback. Practical: Experiments are designed to reflect the topics covered including spectrophotometry, chromatography, flow cytometry.

Mandatory 6 months uninterrupted SIWES training at the 300-level second semester. Work experience in public or private institutions and organisations relevant to the programme and or job market such as hospitals, nursing homes, ambulatory care facilities, physician practices, insurance organisations, health-related research and development firms, pharmaceutical and medical equipment companies.