BME 453
Human Biotechnology
2
Course Description
Students should be able to:
1. apprehend the general principle and practice of biotechnology;
2. explain the structure and function of cell organelles and cellular transport;
3. describe the science of biotechnology and identify its product domains;
4. comprehend the concepts in human genetics and its applications;
5. identify the various natural and laboratory based modifications of DNA;
6. apply human biotechnology in solving human health problems;
7. use molecular biology techniques genetically engineer the animals to improve
sustainability, productivity and suitability for pharmaceutical, agricultural and industrial
applications; and
8. explain how scientific methodologies are used to conduct experiments and develop
products.
Course Outline
Introduction to Biotechnology: Historical background; types, their examples and applications
Biotechnology and human health: pharmaceuticals, diagnosis, vaccines, gene therapy, organ
replacement therapy, nutrition, environmental health, health prevention, etc. Introduction to
Genetic Engineering: history of genetic engineering; cloning; DNA fingerprinting; polymerase
chain reaction; summary of DNA fingerprinting; application of GE in fighting diseases.
Introduction to Tissue Engineering: basic biological concept– cells, organelles; tissue
organisation; tissue dynamics, representative tissue; case studies; barriers to tissue
engineering adoptions.