Blood Transfusion and Transplantation

At the end of this course, students should be able to: 1. list indications for blood transfusion and explain methods of blood storage, anticoagulants and shelf-lives; 2. describe blood component preparation, indications, and rational use of blood; 3. list steps of compatibility testing, bedside transfusion checks, and complications of blood transfusion; 4. enumerate the various types of blood donors with their merits and demerits and explain the donor selection criteria; and 5. describe the process of blood collection and screening and enumerate the recommended mandatory TTIs screened for in Nigeria.

Introduction to red blood cell serology. Antigens and antibodies of ABO and Rh blood group systems, haemolytic diseases of foetus and newborn. Blood donation. Donor recruitment including criteria for acceptance and deferrals for allogenic blood donors. Blood collection and screening for TTIs including HIV–screening and window period. Clinical blood transfusion. Indications for blood transfusionn, blood storage, blood fractionation and component therapy, rational use of blood, blood compatibility testing, bedside pre-transfusion check. Complications of blood transfusion and management. Immediate, delayed, immunological and non- immunological.