General/Radiographic Pathology

At the end of this course, the students should be able to: 1. explain the biochemical, cellular, tissue and organ responses to insults that results to malfunction of the human body; 2. describe At the end of this course the students should be able to the response to injury by various tissues, organs and systems; and 3. identify these morphological changes on images to enable technique modification and quality assessement of images.

Ultrastructure of normal cell, Cell Injury and Death, Degeneration, Necrosis and Intracellular Accumulation, Adaptive Responses: Hypertrophy, Hyperplasia, metaplasia and atrophy, Dysphasia. Disturbances of Fluid Balance. Oedema and Dehydration. Neoplasia: Definition, Classification, Nomenclature, Characteristics, Local and Systemic Effects. Haemorrhage – Causes, Local Effects, Systemic Effects including shock, Thrombosis, Embolism and Infarction. Inflammation: Acute and Chronic Inflammation, Chemical Mediators of Inflammation, Local and Systemic Effects of Inflammation. Healing and Repairing Regeneration, Primary and Secondary Healing, Factors and delay wound healing, Hypersensitivity reactions. Pathologic Calcification. 500 Level