Renal Physiology, Body Fluids and Temperature Regulation

At the end of this course, students should be able to: 1. describe the structure of kidney and nephron; 2. list general functions of kidney; 3. describe GFR and factors regulating it; 4. explain the process of urine formation, filtration, reabsorption and secretion; 5. discuss the processes producing concentrated and diluted urine; 6. describe the regulation of blood pressure by kidneys; 7. list the hormones of kidney; 8. define acidification of urine; 9. conduct renal function tests; 10. discuss renal failure and haemodialysis; and 11. describe micturition reflex and abnormalities of micturition including incontinence.

The skin. Functional anatomy, temperature regulations, abnormalities of temperature regulation. Metabolism, factors regulating metabolism, conditions for measuring basal metabolic rate. Compartmentalization and composition of body fluids. Physiologic anatomy of the kidney, renal circulation and autoregulation. Glomerular filtration. Tubular transport. Urine formation, counter-current system. Water volume and ionic regulation. Acid-base balance. Micturition. Abnormalities of renal function.