Systemic Pathology I

At the end of this course, students should be able to: 1. describe the epidemiology, aetiopathogenesis, morphology, clinical features, investigation, prognosis and management of hypertension, atherosclerosis, ischemic heart disease (angina pectoris, myocardial infarction), valvular heart disease, cardiomyopathies, congenital heart disease, pericarditis, heart failure, hypertensive heart disease, cardiac tumours; 2. explain epidemiology, aetiopathogenesis, morphology, clinical features, investigation, prognosis and management of COLDs, restrictive lung disease (pneumoconiosis, hypersensitivity pneumonitis, sarcoidosis, idiopathic pulmonary fibrosis), pneumonia, PTB, respiratory distress syndromes (neonatal/adult), pulmonary embolism and hypertension, respiratory failure, lung tumours, upper respiratory infections (common cold, pharyngitis, croup, epiglottitis, otitis media); and 3. discuss epidemiology, aetiopathogenesis, morphology, clinical features, investigation, prognosis and management of retinoblastoma, neuroblastoma, nephroblastoma, medulloblastoma, Burkitt’s lymphoma, embryonal rhabdomyosarcoma.

Cardiovascular system. Hypertension. Atherosclerosis. Ischaemic heart disease. Hypertensive heart disease. Valvular heart disease. Heart failure. Cardiomyopathies. Congenital heart disease. Pericarditis. Cardiac tumours. Lymphoreticular system. Acute and chronic lymphadenitis. Lymphoid hyperplasia. Lymphomas. Hyperimmune. Malaria. Splenomegaly syndrome. Other causes of splenomegaly. Respiratory System. COLDs. Restrictive lung disease (pneumoconiosis, hypersensitivity pneumonitis, sarcoidosis, idiopathic pulmonary fibrosis). Tuberculosis. Pneumonia. Respiratory distress syndromes (neonatal/adult). Pulmonary embolism. Pulmonary hypertension. Respiratory failure. Lung tumours. Upper respiratory infections (common cold, pharyngitis, croup, epiglottitis, otitis media). Childhood 218 malignancies. Retinoblastoma. Neuroblastoma. Nephroblastoma. Medulloblastoma, Burkitt’s lymphoma. Embryonal rhabdomyosarcoma. GIT system. Oral cancer. Dental caries. Sialoadenitis. Salivary gland tumours. Tracheo-oesophageal fistula. Achalasia cardia. Hiatus Hernia. Oesophagitis. Oesophageal cancer. Gastritis. Peptic ulcer. Hypertrophic gastropathy. Gastric cancer. Malabsorption. Inflammatory bowel disease. Hirschprung disease. Appendicitis. Intestinal polyps. Colorectal cancer. Hepatobiliary/Pancreas. Hepatitis, yellow fever. Lassa fever. Alcoholic liver disease. Metabolic liver disease. Cirrhosis. Liver tumours. Primary biliary cirrhosis. Sclerosing cholangitis. Cholelithiasis. Cholecystitis. Pancreatitis. Pancreatic tumours. Endocrine System. Diabetes mellitus. Islet tumours of the pancreas. Hyperthyroidism. Hypothyroidism. Thyroiditis. Thyroid tumours. Multiple endocrine neoplasia (MEN). Pituitary and adrenal disorders.