Chemotherapy of Tropical Infections, Disinfectants and Antiseptics

At the end of this course, students are expected to: 1. list the various types of medically-important parasites and their hoists; 2. explain the differences between protozoal and helminth infections; 3. discuss the general principles behind chemotherapy of parasitic diseases in human and animals; 4. discuss the mechanisms of action, adverse effects and contraindications of the major classes of drugs used in the treatment of protozoal and helminth infections; and 5. discuss the properties, chemical composition, classes, mechanisms of action and selection criteria of antiseptics and disinfectants.

Life cycle of malarial parasite. Life cycle of E. histolytica. Pharmacology of drugs used in the treatment of malaria, Amoebiasis, Trypanosomiasis, Leishmaniasis, Helminthiasis. Miscellaneous antimicrobial agents. Chemistry, mechanism of action, selection criteria and uses of disinfectants, antiseptics and sterilants.