APT 301
Principles of Diseases and Pathology
2 Unit(s) (LH 30)
Course Description
At the end of the course, students should be able to:
1. describe the aetiology and pathogenesis of disease processes; and
2. describe the pathological processes that lead to changes in diseased organs and
tissues how these relate to clinical signs and symptoms.
Course Outline
The normal cell and the adopted cell, cell injury and cell death, introductory general and systemic
pathology, characteristics and classification of diseases of various body systems such as
cardiovascular (hypertension, angina pectoris and other vascular diseases, cardiac arrhythmia
and heart failures), endocrinological and highlight the organisational functions, hypophyseal
hormones and pineal gland, ACTH, insulin, glucagon, parathyroid, sex hormones, pregnancy and
lactation; body’s reaction to disease-inflammation, immunity and immunological and genetic
factors in disease, adverse drug reactions. Pathology (pathophysiology, disease processes to a
stage 1 tertiary standard) to include a basic principle and understanding of pathology including
the role of micro-organisms in health and disease. Chronic and infectious diseases (such as fungal,
viral and parasitic), deficiency diseases, protein-calorie malnutrition, vitamins and mineral
deficiency, endocrine, metabolic, neurological and emotional diseases. Neoplasia; diverse drug
reactions as well as the clinical aspects.
Introductory general and systemic pathology – characteristics and classification of diseases
inflammation, wounds, respiratory system, alimentary system, kidneys and urinary tract system,
and many others. Consideration of the pathophysiology of infectious and chronic diseases as well
as cancer.