Clinical Toxicology Pharmacology

At the end of this course, students should be able to: 1. explain the mechanisms of intoxication by heavy metals and the approaches to treatment; 2. describe mechanism, sources and treatments of cyanide poisoning; 3. discuss intoxication with insecticides; 4. enumerate types of insecticides, mechanisms of toxicity and treatments; 5. list classes of snakes and major toxic effects; and 6. describe pharmacology of snake venom.

Clinical Toxicology. Intoxication with heavy metals (mercury, arsenic, lead). Heavy metal antagonists (dimercaprol, EDTA, penicillamine). Cyanide poisoning and treatment. Intoxication with insecticides. Chlorinated hydrocarbons, organophosphates and cholinesterase reactivators. Pharmacology of snake venoms. Elapid venoms. Viperid venoms.