Cell Biology, PH and Buffer

At the end of this course, students should be able to: 1. discuss the role of electro transport chain and oxidative phosphorylation in the generation of ATP; 2. define genetic; 3. explain structure of chemistry and function of normal living cell; 4. discuss metabolism of proteins; 5. describe carbohydrates, nucleic acids and lipids; 6. illustrate basic biochemical importance; and 7. apply biochemical knowledge in the clinics. 51

Introduction to Biochemistry. Review of concepts in chemistry applicable to biological systems, chemical bonds covalent and ionic, biomolecules, elementary thermodynamics, reaction equilibria. Henderson equation application. Water, physical, biological and chemical properties. Acid-base chemistry, buffer systems and application to living systems. Introduction of terms used to describe acid-base disorders in the body, academia, alkalemia, acidosis and alkalosis. Enzymes, their properties and kinetics. Diversity of biomolecules, carbohydrates, lipids, proteins, amino acids and nucleic acids in nature. Structure, properties, and biochemical/biological functions of carbohydrates. Lipids, amino acids, proteins and nucleic acids.